Some efficacy and application of magnolol

Its physical and chemical properties are similar to white powder.

Its melting point is 102℃.

Soluble in benzene, chloroform, acetone and other common organic solvents.

Hardly soluble in water, soluble in dilute alkali solution.

Pharmacological action: Magnolol is a kind of diphenyl-C compound.

This product is a white powder, fragrant, strong irritant, slightly bitter.

It is the main active ingredient of Magnolia officinalis.

Small molecular natural product extracted from the bark, root bark and branch bark of Magnoliaceae or Magnolia officinalis.

It has anti-inflammatory, anti-bacterial, protective cardio-cerebrovascular system, anti-anxiety and depression, muscle relaxation, anti-oxidation, improving gastrointestinal dysfunction and anti-tumor effects.

Some efficacy and application of magnolol

Magnolol aqueous extract has obvious turmeric - like effect.

The alcohol extract of Magnolia officinalis can reduce grip strength and strongly inhibit spasticity induced by strychnine and tetrandrine.

It can relieve intestinal spasm induced by barium chloride and pilocarpine and inhibit the contraction of isolated guinea pig bronchial smooth muscle induced by histamine.

A water-soluble Magnolia officinalis alkaloid (Magnolia officinalis Curcumine) was isolated from Magnolia officinalis.

It relaxes the striated muscles and blocks the transmission of pulses through the motor endplate.

Therefore, it has a neuromuscular blocking effect.

Magnolol has antibacterial effect on gram-positive bacteria such as staphylococcus, pneumococcus, hemolytic streptococcus and gram-negative bacteria such as dysentery bacillus, typhoid bacillus, escherichia coli and subtilis bacillus.

Magnolia ether extract can reduce the spontaneous activity of mice and antagonize the stimulation of methamphetamine or apmorphine.

Honokiol and imarulol also had significant central inhibitory effects.

Magnolol had a complete inhibitory effect on spinal reflex in mice, and 0.25~1g/kg ether extract had a central inhibitory effect on any reflex.

The results showed that magnolia magnolia crude products and ginger products had anti-gastric ulcer effect on pyloric ligation and stress type acute experimental gastric ulcer model rats, among which ginger products had the most obvious effect.

Magnolol100mg/kg intraperitoneal injection or subcutaneous injection can inhibit water impregnation to inhibit stress ulcer, thioethanolamine ulcer and pyloric ligation ulcer, and can antagonize the central gastric acid secretion stimulant.

Honokiol is an effective cosmetic free radical trapping agent, which is very effective against HO type free radicals.

PPAR has high activity and has anti-apoptotic effect. Inhibition of NF-B cells proves that PPAR can improve the function of skin immune cells. It has anti-inflammatory and anti-ulcer properties.

In oral hygiene products, can be used to prevent and treat acne;

In oral hygiene products, can be used to prevent and treat acne;

In oral hygiene products, can be used to prevent and treat acne;