The main value of artichoke extract

Main valueedit

Treat indigestion

In Europe, artichoke is an herbal medicine that has been used to treat indigestion. Artichoke extract is used to treat gastrointestinal diseases including abdominal pain, bloating, and nausea.

Lowering blood lipids and anti-atherosclerosis

Many experiments have shown that artichoke extract can lower blood lipids, mainly by affecting the synthesis and decomposition of cholesterol and lipids in the liver to regulate lipid levels, thereby preventing the occurrence of atherosclerosis.

Liver protection and antioxidant function

The research on the antioxidant function of artichoke has mostly focused on leaf extracts. The antioxidant capacity of polyphenol compounds isolated and extracted from artichoke is found to be mainly determined by the number of hydroxyl groups on the aromatic ring. The more hydroxyl groups, the stronger the antioxidant capacity. In addition, the second hydroxyl group located in the ortho and para positions can also increase its antioxidant capacity. The test results show that the EC50 values of 1 g of dried artichoke extract on DPPH and FRAP are equivalent to 29.2 mg and 62.6 mg VC, and 77.9 mg and 159 mg VE, respectively, and have a good anti-oxidation effect of low-density lipoprotein. .

The results of the in vitro antioxidant test of rat hepatocytes showed that the aqueous extract of 0.001 mg/ml can reduce the content of MDA without affecting the level of glutathione (GSH) in hepatocytes. On the contrary, it reduces the loss of GSH and GSSG. The loss of. Shows that artichoke extract has a strong antioxidant effect. Therefore, it is inferred that the antioxidant effect of the extract is the main reason for its liver protection and liver regeneration effects.

Antimicrobial effect

The antimicrobial activity of chlorogenic acid, cynic acid, luteolin-7-rutinoside and cynchoside in artichoke is relatively high, and the antifungal activity is stronger than the antibacterial activity.

Other value

Artichoke leaf extract, especially the flavonoids in it, can regulate the gene expression of NO enzyme in human epithelial cells, promote the synthesis of NO, and prevent the occurrence of cardiovascular diseases. The cynaropicrin contained in artichoke has an anti-spasmodic effect. In addition, artichoke can improve intestinal motility, promote the contraction of the intestinal wall, and enable the intestinal material to be transported faster, thereby preventing constipation.